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Recent Posts
Tregs in the tumor microenvironment: A friend or a foe?
By admin
/ September 1, 2020
CD4+ Regulatory T (Treg) cells suppress excessive immune responses thus maintain sanity in the host immune system. Cancer cells take…
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Death by Dimensions
By admin
/ August 11, 2020
In this big data era, the importance of statistics does not need any mention. It helps us make sense of…
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EZH2 inhibitors sensitize HR proficient ovarian cancers to PARP inhibitors
By admin
/ April 14, 2020
Homologous recombination (HR) is a precise DNA repair mechanism, which is impaired in BRCA-mutant tumors. PARP inhibitors are effective against…
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Cancer Vaccines — A Promising Prospect
By admin
/ February 8, 2020
Cancer vaccines Since the discovery, vaccines have proven effective in fading off some of the deadliest diseases, saving a countless…
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The Correlation Conundrum!
By admin
/ December 18, 2019
The recent shift in funding policies favoring translational-over-basic research has forced researchers to associate their gene/protein of interest to diseases…
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Kaplan-Meier plot and the survival statistics
By admin
/ December 9, 2019
Once every five years, Nepal hosts a festival where Hindu devotees from Nepal and India gather in a small village…
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Puzzling out the STING activation in cancer
By admin
/ December 3, 2019
Following up on the previous blog (STING the Cancer). Here, I summarize a recent paper from Linda et al. published…
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How to turn cancer cells into fat?
By admin
/ November 11, 2019
Given a choice between gaining some fat vs having metastatic cancer, what would you choose? For a cancer patient, this…
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STING the Cancer
By admin
/ May 7, 2019
If you had attended the American Association of Cancer Research (AACR) annual meeting this year (2019), you must have noticed…
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Microbiota to the cancer rescue
By admin
/ March 14, 2019
Immunotherapy has changed the landscape of cancer treatment with complete tumor remission in a subset of patients. While immense efforts…
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